Coolproteomics.com|It’s all about proteins, isn’t it?

Have you ever spent time in a crowded city on a busy street corner just watching? Watching people?

Close your eyes and see it in your mind. You’re at the corner of Fifth and Park Avenues in New York City… it’s the summer and it just rained. You have to meet someone for dinner so you call to get directions and exchange information. On the way out of the office you smoke a joint, buy flowers from a vendor, bump into someone who quietly pick-pockets your wallet while you give some money to a street artist… and you continue to watch the people around you. Some of them are more attractive then others, you think to yourself, and then one comes along and you hug tightly… you can feel the chemistry.

Now, think about a cell… go deep inside and make yourself tiny. Really tiny. Can you see the different macromolecules floating around, some hurrying to get somewhere… some hanging with the wrong crowd, free radicals, roaming proteases, foreign small molecules, substrates. And then a few bump into each other and hang out for a while, while others avoid each other with a vengeance. You watch as one decent sized multivalent protein leans against the cell membrane and rings the doorbell. A giant vacuole pops open and with its lipid lips swallows it whole. Shock is in the air. Most of the proteins seem to know where they’re going, but some just hang around like they’re waiting for a bus.

They are born, one amino acid at a time. They fold, unfold, perform a function and then die… chopped up by another protein like a mortician preparing a body.

And life goes on.

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We live in a cool world. This blog is about a slice of that world… the science and business surrounding the study of proteins… proteomics. For those who think that’s boring, you just haven’t lived yet.

So what about proteins? Proteomics. Protein chemistry. Molecular proteomics. Protein shakes. There’s some great stuff happening that will change the world in a few years… and I’ll give you an advanced look at who’s doing it, where it’s coming from and the direction it’s headed.

So we’ll be drilling deep… from the anxiety of going bottoms-up or top-down… to the thrill of hovering at the 30,000 feet level talking ethics. That’s about the extent of my plan.

I’m a direct talk guy… I’ll tell you the way I see it. I look forward to your comments and if I ever offend, it is never intended.

In the next post I’ll talk about ASMS and my impressions on what I saw, and I’ll also tell you a bit more about me and my background.

Enjoy the weekend!

PS… that beautiful bay in the picture above is the view I had when I created CoolProteomics.

Proteomics is Cool!! Isn’t it?